Sr. Scientist I, Molecular and Cellular Biology

Job Description

Job DescriptionSalary: $110,000 - $120,000/year

Job Overview

BPS Bioscience Inc. is a leading provider of recombinant proteins, assay kits, and recombinant cell lines for drug discovery. We are seeking an exceptional scientist, with a strong background in enzymology, enzyme kinetics, protein/protein interactions, and fluorescence and luminescence-based assays.

We are seeking a highly skilled Senior Scientist I with deep expertise in antibody generation to join our Molecular and Cellular Biology team. This position plays a critical role in driving research and development efforts, with a primary focus on the design, expression, engineering for multiple targets, purification, and optimization of antibodies, including phage display, single B cell isolation, humanization, and stable cell line generation. The ideal candidate will have strong industry experience and be adept at independently designing and executing experiments at a high standard.

Responsibilities:

• Lead and execute projects related to antibody generation, including:
  
  • Antibody design and engineering (e.g., humanization, affinity maturation, bispecific antibody)
  • Molecular cloning and vector design
  • Transient and stable expression in mammalian system
  • Antibody purification using affinity chromatography and other techniques
• Develop and optimize stable cell lines for antibody production
• Utilize fermentation systems for antibody expression (small- to mid-scale)
• Evaluate and integrate new technologies to enhance R&D capabilities
• Participate in team meetings, project planning, and cross-functional collaborations

• Design and perform cell-based functional assays to characterize antibody activity
• Present research findings internally and externally, including at scientific conferences
• Maintain rigorous documentation and ensure high standards of data integrity
• Maintaining excellent working relationships with partners throughout the company.
• Maintaining updated and well-organized lab notebooks.
• Other tasks and duties as assigned.

Requirements:

• A Ph.D. degree in Molecular Biology, Cell Biology required.
• Minimum 3 - 5 years industry experience focused on antibody generation required
• The candidate must have proven experience performing enzyme kinetics and assay optimization.
• Proven track record in antibody discovery and development, including engineering and functional validation
• Extensive experience with phage display, mammalian cell culture, sterile technique, and molecular biology methods
• Proficiency in downstream processing including protein purification and analytical characterization
• Strong problem-solving skills and ability to manage multiple projects in parallel
• Excellent written and verbal communication skills
• Team-oriented with a collaborative mindset and attention to detail

Benefits!

• 401k with 4% company match
• Medical/Dental/Vision health insurance plans
• Vacation and paid holidays
• Companywide lunches provided quarterly

BPS Bioscience is an equal opportunity employer, without regard to race, color, religion, age, gender, sexual orientation, disability, or any other characteristic protected by applicable law.