(Sr.) Research Assistant - In Vivo Pharmacology

Job Description

Aperture Therapeutics is advancing breakthrough therapeutics for age-related neurodegeneration, leveraging insights from human genetic diversity. We invite skilled scientists to join our mission-driven team to make a meaningful impact on patient lives.

As a member of our Neuroinflammation research group, the (Senior) Research Assistant will play a crucial role in the pre-clinical evaluation of innovative therapies using rodent models. The ideal candidate will bring advanced technical expertise, a collaborative spirit, and a passion for translating science into therapies. We are committed to the ongoing professional growth of highly driven and independent scientists.

Key Responsibilities:

• Conduct in vivo pharmacological studies using rodent models to support drug discovery and development
• Perform a wide range of compound administration techniques, including ICV, IT, IV dosing
• Execute tissue collection, dissection, and processing for subsequent histopathological and biochemical analyses
• Apply proficiency in quantitative assays such as ELISA/MSD, qRT-PCR, and IHC to analyze experimental outcomes
• Maintain meticulous laboratory records and contribute to high standards of scientific rigor and data integrity
• Collaborate closely with cross-functional scientific teams, communicating results and contributing to research strategy

Qualifications:

• B.Sc. or M.Sc. in Cell Biology, Molecular Biology, Biochemistry, Neuroscience, or a related discipline
• Minimum of three years’ hands-on experience in rodent handling and colony management
• Demonstrated expertise in various drug administration techniques
• Advanced skill in tissue dissection and preparation for diverse analytical assays
• Proficiency in quantitative biochemical techniques
• Highly organized with exceptional critical thinking, troubleshooting, and communication abilities

Benefits for Full-Time Employees:

• Competitive salary commensurate with experience and achievements
• Comprehensive benefits including medical, dental, vision, and life insurance
• Commuter benefits

If you are passionate about helping to advance the edge of innovation and developing impactful treatments for age-related diseases, we encourage you to apply and grow with us at Aperture Therapeutics.