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<h3>Job Description</h3>
BEAUTY/COSMETIC RESEARCH &amp; DEVELOPMENT MANAGER!
THIS POSITION
<ul>
<li>Responsible for independently identifying the needs of the brands within R&amp;D, including formula, package and process.</li>
<li>Support Leads in their need to guide the spirals.</li>
<li>Establishing schedules for required R&amp;D activities with special emphasis on work-place efficiency.</li>
<li>Responsible for attending timeline meeting with the cross functional teams.</li>
<li>Assist formulators in identifying high risk/novel technologies and coordinate scale-ups and line trials for new products and formulations.</li>
<li>Make critical observations, solve problems, and proactively make decisions in pursuing the direction of projects</li>
<li>Start learning the skill of writing and training for Lab SOP’s.</li>
<li>Develop industry network that can be leveraged to enable the innovation process, including participation in industry organizations such as SCC and developing relationships with raw material suppliers</li>
<li>Adhere to company safety guidelines at all times</li>
<li>Support all activities of the R&amp;D Team.</li>
</ul>
 
NEEDED
<ul>
<li>BS/BA in Chemistry/related field or equivalent years of relative experience.</li>
<li>3-5 years of experience minimum</li>
<li>Experience working with and fully understand lab environment is required</li>
<li>Ability to successfully lead and communicate with cross functional teams.</li>
<li>Possess good GMP knowledge</li>
<li>Ability to work well under tight deadlines while managing multiple projects; use a good judgement in difficult situations</li>
<li>Self-starter with high level of initiative and possess the ability to make decisions in order to maintain progress on projects</li>
<li>Understand the right message medium and uses active listening skills</li>
</ul>

Research & Development Manager-Beauty-San Fran

<h3>Job Description</h3>
About Us
Seawolf Therapeutics is a Series A company based in San Diego, CA. We are an innovative and collaborative team developing DNA-based medicines that will be first-in-class and best-in-class long-acting therapeutics for patients living with unmet medical needs. Come join our team and be an agent of change.
 
Overview of the Role
We are seeking a Research Associate/Sr. Research Associate to join our Delivery Technology team and facilitate our formulation development efforts. This is a hands-on, on-site laboratory role, with approximately 80% lab-based work and 20% dedicated to data entry and experiment planning. This individual will be actively engaged in developing the core delivery technology for advanced nucleic acid-based therapeutics. A key point of focus will be to produce highly intricate lipid nanoparticle (LNP) formulations, which includes optimizing the LNP compositions and troubleshooting the scale-up of the LNP formulation process. The ideal candidate will possess the skills necessary to independently prepare formulations of lipid nanoparticles for the delivery of nucleic acid-based pharmaceuticals. This role additionally requires a passion for scientific discovery, interdisciplinary collaboration, good organization and record keeping, and the ability to present and discuss work across functional teams.
 
Key Responsibilities
<ul>
<li>Support the development of unique and novel nucleic acid-based formulations.</li>
<li>Prepare samples for internal studies, ensuring timely and accurate transfer of materials.</li>
<li>Characterize product profiles for process optimization and batch-to-batch reproducibility.</li>
<li>Maintain meticulous documentation of all experimental data, procedures, and protocols.</li>
<li>Maintain organized storage and inventory of supplies and materials.</li>
<li>Collaborate with a team of scientists to creatively solve problems and drive innovation.</li>
<li>Maintain high standards for scientific integrity and accountability.</li>
<li>Communicate across departments and support project teams.</li>
</ul>
 
Qualifications
Education and Experience
<ul>
<li>BS/MS in chemistry, chemical engineering, bioengineering or related field with at least 2 years of relevant industry experience.</li>
</ul>
Technical Skills
<ul>
<li>Prior hands-on experience with the following:</li>
<li>Nano-formulation of nucleic acid-based therapeutics, filtration techniques, characterization of nanoparticulate matter. </li>
<li>Pipetting, buffer preparation, and using an analytical balance.</li>
<li>HPLC, UV-Vis, and plate-based fluorescence assays.</li>
<li>Able to conduct self-directed research and thrive in a fast-paced entrepreneurial setting with a diverse team of coworkers.</li>
<li>Strong troubleshooting and problem-solving skills for experimental and equipment-related issues.</li>
<li>Proficiency in Microsoft Suite (Excel, Word) for data documentation and analysis.</li>
</ul>
 
Organizational &amp; Soft Skills
<ul>
<li>Strong organizational skills, attention to detail, and meticulous data documentation.</li>
<li>Ability to prioritize multiple tasks while maintaining accuracy.</li>
<li>Effective verbal and written communication skills for cross-functional collaboration.</li>
<li>Exceptional problem-solving skills, outstanding interpersonal skills, creativity, enthusiasm, reliability.</li>
<li>Flexibility to adapt to evolving project priorities in a dynamic environment.</li>
<li>A team-oriented, startup mentality, willing to take on multiple responsibilities.</li>
<li>Scientifically curious, paired with a strong work ethic and grit.</li>
</ul>
 
Authorization
Applicants must have authorization to work in the U.S.
 
The anticipated salary range for candidates who will work in San Diego, CA is $60,000 to $100,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc.
 
Seawolf provides competitive salaries and an excellent benefits package including medical, dental, vision, life insurance, 401K, stock options and bonus.

Research Associate/Sr. Research Associate, Formulation Development

<h3>Job Description</h3>
Computational Biologist - IBD Research
Location: Fully Onsite - San Francisco, CA
Type: 3 month Contract
Pay Rate: $38-$50/hr 
Schedule: Monday-Friday, 8-5
Start Date: Immediate
 
About the Role
We are seeking an experienced Computational Biologist with strong immunology expertise to join our innovative research team. In this role, you will establish robust and integrated data-driven analysis frameworks that leverage multimodal data (molecular, cellular, clinical, and imaging) in Inflammatory Bowel Disease (IBD).
 
Core Responsibilities
<ul>
<li>Develop and implement generalized procedures for summarizing molecular, cellular, and clinical information on potential therapeutic targets.</li>
<li>Maintain and apply a unified computational infrastructure to review targets in both early and late research pipeline phases.</li>
<li>Design and implement strategies for multimodal IBD data integration to identify novel targets and biomarkers.</li>
<li>Apply advanced computational methods, including AI/ML and foundation models, for data integration across diverse IBD datasets.</li>
<li>Critically interpret computational results within the context of IBD pathobiology.</li>
<li>Translate data-driven findings into actionable recommendations for target and biomarker discovery efforts.</li>
<li>Collaborate with cross-functional teams to ensure seamless integration of computational approaches with experimental workflows.</li>
</ul>
 
Qualifications
<ul>
<li>PhD in Computational Biology, Bioinformatics, Immunology, or related field.</li>
<li>Specialized knowledge of IBD pathogenesis and the current IBD therapeutics landscape.</li>
<li>Strong background in immunology with in-depth knowledge of immune pathways and mechanisms.</li>
<li>Demonstrated expertise in computational biology and bioinformatics.</li>
<li>Experience applying AI/ML methods to analyze multimodal omics and clinical data.</li>
<li>Proficiency in using and fine-tuning foundation models for biological data analysis.</li>
<li>Experience with multimodal data integration techniques.</li>
<li>Strong programming skills in languages commonly used for bioinformatics (e.g., Python, R).</li>
</ul>
 
This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!

Computational Biologist - IBD Research

<h3>Job Description</h3>
We are looking for a Computational Scientist (Biology) who works at the intersection of high-dimensional biological data, cell biology, and ML. You’ll help build predictive models from high-content imaging and functional biochemical assays to better predict human toxicity. The ideal candidate will have experience transforming noisy biological datasets into actionable insights, uncovering novel biological signals related to drug safety, and performing error analyses on ML models to understand biological mechanisms.
 
Culture:
<ul>
<li>High-agency, high-intensity: They want people who see what matters and do it—no handholding, lots of initiative.</li>
<li>Obsessive and irrational ambition: They admire candidates who could be in big tech but choose a harder path because they want meaning, challenge, and impact.</li>
<li>Craft-first mentality: Deep mastery of your field—biologists who code, engineers who care about biology. You need to love the work itself.</li>
<li>Curiosity-driven: They value people who dig into weird, niche hobbies and demonstrate intense curiosity across disciplines.</li>
<li>Founding mindset: Think like an owner. They're building something from scratch and want people who act like it's theirs.</li>
<li>Not for coasters: If you're looking for stability, predictability, or a 9–5 box-checker job, this isn't it.</li>
</ul>
 
Core technical responsibilities include:
<ul>
<li>Analyze and interpret large-scale multimodal toxicity datasets.</li>
<li>Develop custom algorithms to extract signals from high-content imaging, including Cell Painting and cell morphology data.</li>
<li>Design and optimize novel assays that generate scalable, predictive datasets.</li>
<li>Perform rigorous statistical analyses (curve fitting, dimensionality reduction, modeling, traditional imaging algorithms).</li>
<li>Collaborate with ML researchers to enhance predictive accuracy by integrating biological insights and experimental data.</li>
<li>Implement and manage quality control pipelines for high-throughput, imaging-based screens.</li>
</ul>
 
Preferred technical stack and experience:
<ul>
<li>Python (Pandas, NumPy), Jupyter Notebooks</li>
<li>Image analysis tools like CellProfiler and Cellpose</li>
<li>Deep experience in assay development, high-throughput screening, and automation</li>
<li>Experience analyzing imaging-based phenotypic screens or cell painting datasets</li>
<li>Strong understanding of biology across systems (e.g., liver, heart, kidney, immune)</li>
<li>Demonstrated ability to bridge wet lab protocols and machine learning pipelines</li>
</ul>
 
The right candidate is likely a biologist who taught themselves to code to handle their own data, with a passion for both technical rigor and biological discovery.

Founding Computational Scientist (Biologist)

<h3>Job Description</h3>
About Nonfiction Laboratories:
Nonfiction Laboratories is a biotechnology startup based in San Francisco, California. We’re a science and invention driven company, developing a new platform for magnetogenetic control over therapeutic proteins. We want to be able to take any therapeutically-useful protein and be able to turn its activity on/off using magnets. By building therapeutics that can be turned on when and where you need the drug, we spare healthy tissue while targeting disease tissue harder. The potential level of impact here is significant and uncommon — treatments that are more safe, precise, and effective, across a wide range of diseases. We want to open up an entirely new modality and field of research.
To pull this off, we need the most talented inventors, engineers, and scientists we can find. Expect lots of hard work, at the bleeding edge of a new field. We love to collaborate with external colleagues, including many excellent academic laboratories. We value our friendly, invention-focused culture. Doing new things is hard! If you are up to the challenge, please consider applying.
The Role:
Nonfiction Laboratories is seeking a talented and motivated candidate to join our team as a Research Associate, focusing on scaling our workflows around building and evaluating our protein engineering libraries. You will play a critical role in industrializing our existing protein engineering workflows, troubleshooting, and generally making our workflows more robust.
Required:
<ul>
<li>Molecular Biology — PCR (including primer design), minipreps, gels and gel extraction, proper pipette technique,&nbsp;E. coli&nbsp;and yeast culture and transformation.</li>
<li>Cloning — Gibson Assembly, Golden Gate. Colony PCR. Ability to interpret a plasmid map, review a construct description, and select the primers, gene fragment sequence, and protocol to build the desired construct.</li>
<li>Experience using and maintaining an electronic lab notebook (ELN) to track tasks, inventory status, and periodic project updates.</li>
<li>Ability to work on-site in our laboratory in San Francisco.</li>
</ul>
Nice to have:
<ul>
<li>Experience running ELISAs, with the ability to troubleshoot. Bonus for kinetic and cell-based ELISAs.</li>
<li>Experience independently planning library diversification protocols (e.g., site-directed mutagenesis, linker screens, transposase libraries).</li>
<li>Familiarity with fluorescent microscopy.</li>
<li>Sequencing prep.</li>
<li>Experience with protein purification preps.</li>
<li>Experience with mammalian cell culture.</li>
<li>Basic programming skills (Python) for data analysis, primer design, and automation scripting.</li>
</ul>
Equal Opportunity
Nonfiction Labs is an equal opportunity employer. We welcome applicants from all backgrounds and do not discriminate on the basis of race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

Research Associate

<h3>Job Description</h3>
About Enlaza Therapeutics: 
Enlaza Therapeutics is a growing biotech company developing an innovative synthetic biology platform to create a disruptive new class of biologic therapeutics. We are dedicated to the development of these novel therapies to help patients suffering from cancer and other serious diseases.
 
Role Description: 
We are seeking an experienced senior scientist skilled in developing and qualifying target binding and cell-based potency assays for protein biologics and conjugates. You will work closely with research teams to advance assays from discovery to CMC development. In this hands-on role, you will lead the development and transfer of potency assays to CDMOs, overseeing their implementation for lot release, stability, and characterization to support clinical manufacturing.
 
Responsibilities:
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Develop GMP QC-compatible target engagement assays to support release and stability testing of covalent biologics.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Develop GMP QC-compatible cell-based assays measuring the potency of covalent biologics for different modalities in support of release and stability testing.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Culture, maintain, and generate well-documented banks of cell lines required for assay development.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Identify and manage critical reagents needed to develop and execute assays.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Author and/or review technical documents for method development, transfer, verification/qualification protocols and reports.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Review GMP release and stability testing results for potency assays. Support OOS/OOT root cause analysis, QC data review, batch release processes, and deviations/investigations at GMP facilities.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Collaborate with the CDMO to support reference standard qualification for bioassays.
 
Requirements:
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Advanced degree (PhD or MS) in biology, biochemistry, or a related field.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A minimum of 5 years of industry experience in potency assay development.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Proven hands-on experience in the development and qualification of recombinant and cell-based potency assays including but not limited to those designed to measure target binding and induction of drug-dependent signaling including cytotoxicity for GMP implementation.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Experience with data analysis software such as PRISM, Softmax Pro, or similar tools.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Strong ability to engage and communicate effectively with cross-functional internal teams and external CDMOs.
 
Additional Experience Preferred but Not Required:
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Previous work with CDMOs and involvement in regulatory submissions is a plus.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Experience with process impurity testing, including assays for bioburden, host cell proteins and DNA, and leached protein A.
 
Compensation:
In addition to a competitive compensation package with stock options, the company also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance.
 
Job Type: 
Full-time
 
Annual Salary:
$145,000.00 – 165,000.00 per year 
 
Supplemental Pay Types:
Bonus pay
 
Benefits:
<ul>
<li>401(k)</li>
<li>Dental insurance</li>
<li>Employee assistance program</li>
<li>Flexible schedule</li>
<li>Flexible spending account</li>
<li>Health insurance</li>
<li>Life insurance</li>
<li>Parental leave</li>
<li>Relocation assistance</li>
<li>Retirement plan</li>
<li>Vision insurance</li>
<li>End of year shutdown</li>
</ul>

Senior Scientist - Potency Assay

<h3>Job Description</h3>
ML Applied Scientist
 
My client is a biotech company using synthetic biology and AI to engineer microbes that convert carbon dioxide into valuable chemicals and materials. Their work focuses on creating sustainable, carbon-negative solutions for industries like fuels, polymers, and specialty chemicals.
 
About the job
Responsibilities
<ul>
<li>Work on in-house protein language models — design, build, test</li>
<li>You will be implementing your own ideas</li>
<li>Work with the lab team to produce the best proteins possible</li>
<li>You will be expected to be deep in the THEORY and Implementation</li>
<li>Not looking to hire any “ML engineers” or “Idea people”</li>
<li>Work with the team on all of the above and more!</li>
</ul>
 
Qualifications
<ul>
<li>PhD/Masters required in Computer Science/Statistics/Machine Learning/Math.</li>
<li>Publication(s) in Math and/or THEORETICAL Machine Learning</li>
<li>Preferred venues: NeurIPS, ICML, ICLR, AISTATS, UAI, JMLR/TMLR, IEEE TIT/PAMI, Annals of Math/Stats</li>
<li>Has led/initiated their own research processes and is comfortable in a fast-paced environment.</li>
<li>Must know how to code well</li>
<li>Strong math background.</li>
<li>My client is an early-stage startup, and things will break. They are looking for someone who is willing to roll up their sleeves and fix things.</li>
</ul>
 
 
Benefits
<ul>
<li>Competitive base pay + equity options (0.5-1.5%).</li>
<li>Full health and dental covered</li>
<li>Based in SF, can cover relocation costs</li>
</ul>

ML Research Scientist

<h3>Job Description</h3>
About Us
LTZ Therapeutics is an immunotherapy-focused biotech company engaging in the development of
novel therapies to improve clinical outcomes in patients with cancer and other diseases with an unmet clinical need. Our mission is to spearhead the discovery and development of the next generation of innovative immunotherapies for cancer.
 
We are seeking a highly motivated Research Associate in the Biology department. The position is full-time, on-site, and located at our headquarters in Redwood City, CA. The ideal candidate is an individual who is interested in working in a fast-paced, dynamic, and highly collaborative biotech environment with a willingness and ability to take on new challenges successfully. The candidate will be part of a cross-functional project team working on early drug development.
 
Responsibilities
 
<ul>
<li>Execute standard immunological assays (cell proliferation, cytokine analysis, phenotyping) using a variety of methods (plate-based assays, ELISA, flow cytometry, cell reporter assays)</li>
<li>Creatively adapt standard assays or develop novel assays to test the unique biology of our platform.</li>
<li>Isolate and analyze cell subsets of interest from various tissues or mixed cell suspensions.</li>
<li>Support PK/PD and biomarker analysis as needed.</li>
<li>Present data at regular group meetings and recommend next steps.</li>
<li>Document research activities and findings in electronic laboratory notebooks and reagent registries in keeping with the highest industry standards.</li>
<li>Exhibit excellent analytical, organizational, communication, and time management skills.</li>
<li>Lab activities will be ~75% time.</li>
</ul>
Required Experience/Qualifications
<ul>
<li>BA/BS or equivalent in biology, immunology, or a related discipline with 4+ years of relevant industry or academic research experience; MS degree or equivalent in biology, immunology, or a related discipline and 2+ years of experience conducting original research.</li>
<li>Deep understanding of immunology.</li>
<li>Experience developing immune assays and working with primary immune cells (B, T, myeloid, and NK) is required.</li>
<li>Proficiency in running multi-parameter flow cytometry panels, analysis of immune cell function, and immune cell isolation.</li>
<li>Skilled in executing assays such as binding, ADCC/ADCP, internalization, and/or various immunoassays to assess complex biology.</li>
<li>Excellent communication and interpersonal skills, enthusiasm and curiosity in science, and the ability to thrive in a dynamic cross-functional environment.</li>
<li>Experience with drug discovery and/or early development.</li>
<li>Experience with bioinformatics/computational biology tools would be a plus.</li>
</ul>
Skills
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Excellent laboratory skills.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Excellent data analysis and organizational skills.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Excellent communication skills.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Ability to work independently and as part of a team.
Benefits:
 
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Competitive compensation package including base salary, annual bonus, stock options and 401k.
·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Competitive benefits package in healthcare, life insurance, and paid time off
 
EEO Statement:

LTZ Therapeutics is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, or sexual orientation.
Orientation, gender identity, national origin, disability, or protected veteran status.
 
Please send your CV to:
Kathy Zeng, <a href="mailto:kathy.zeng@ltztherapeutics.com" target="_blank">kathy.zeng@ltztherapeutics.com</a>
Priti Singh, <a href="mailto:priti.singh@ltztherapeutics.com" target="_blank">priti.singh@ltztherapeutics.com</a>

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